BIO421: Immunology

Missouri Western State University

• Course syllabus/lecture schedule
• Lab syllabus

• Literature Review paper instructions and deadlines

• Guide to using EndNote reference managing software

• Current literature papers (for class presentation and quiz)...

Thursday, March 1: Proteasome paper and TCR Signaling paper (figure assignments given in class)

Thursday, March 29: T cell development paper and B cell development paper (figure assignments given in class)

Lecture topic PowerPoint slides

• Basic Concepts in Immunology

• Innate Immunity

• Ab and TCR Structure

• Ab and TCR Genetics

• Antigen Presentation

• Signaling

• Lymphocyte Development

• T cell Immunity

• Humoral Immunity

• Host Defense Systems (adaptive immunity)

• Failures of Host Defenses

• Allergies and Hypersensitivities (moved to begin on 4/16/07)

• Autoimmunity and Transplantation (cancelled)

• Manipulation of Imm. Response

• Evolution of Imm. Response

CLASS REVIEW...in the form of Jeopardy!, adapted from Brian Jackson's game to suite our class. (Focus on single Jeopardy!, the double Jeopardy! board is not configured for our class.  Don't over-study on just the game, use your old exams and new class notes.)

Immunology Lab Techniques

(Student group PowerPoints)

• Flow Cytometry

• ELISA

• Western Blot

• Monoclonal Antibody Production

• Immunohistochemistry

• Real-Time Quantitative PCR

• Animal Models used in Immunology Research (SCID, Nude, transgenic mice)